Mzt1/Tam4, a fission yeast MOZART1 homologue, is an essential component of the γ-tubulin complex and directly interacts with GCP3Alp6
Identifieur interne : 000242 ( Main/Exploration ); précédent : 000241; suivant : 000243Mzt1/Tam4, a fission yeast MOZART1 homologue, is an essential component of the γ-tubulin complex and directly interacts with GCP3Alp6
Auteurs : Deepsharan K. Dhani [Royaume-Uni] ; Benjamin T. Goult [Royaume-Uni] ; Gifty M. George [Royaume-Uni] ; Daniel T. Rogerson [Royaume-Uni] ; Danny A. Bitton [Royaume-Uni] ; Crispin J. Miller [Royaume-Uni] ; John W. R. Schwabe [Royaume-Uni] ; Kayoko Tanaka [Royaume-Uni]Source :
- Molecular Biology of the Cell [ 1059-1524 ] ; 2013.
Abstract
Fission yeast MOZART1 homologue Mzt1 associates with γ-tubulin and is found at MTOCs. It plays an essential role in microtubule regulation, as well as in septum formation and cytokinesis. Recombinant Mzt1 interacts directly with GCP3Alp6. This interaction may assist MTOC activity of the γ-tubulin complex.
Url:
DOI: 10.1091/mbc.E13-05-0253
PubMed: 24006493
PubMed Central: 3814152
Affiliations:
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Dhani</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Biochemistry, University of Leicester, Leicester LE1 9HN, United Kingdom</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Biochemistry, University of Leicester, Leicester LE1 9HN</wicri:regionArea><wicri:noRegion>Leicester LE1 9HN</wicri:noRegion></affiliation></author><author><name sortKey="Goult, Benjamin T" sort="Goult, Benjamin T" uniqKey="Goult B" first="Benjamin T." last="Goult">Benjamin T. Goult</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Biochemistry, University of Leicester, Leicester LE1 9HN, United Kingdom</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Biochemistry, University of Leicester, Leicester LE1 9HN</wicri:regionArea><wicri:noRegion>Leicester LE1 9HN</wicri:noRegion></affiliation></author><author><name sortKey="George, Gifty M" sort="George, Gifty M" uniqKey="George G" first="Gifty M." last="George">Gifty M. George</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Biochemistry, University of Leicester, Leicester LE1 9HN, United Kingdom</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Biochemistry, University of Leicester, Leicester LE1 9HN</wicri:regionArea><wicri:noRegion>Leicester LE1 9HN</wicri:noRegion></affiliation></author><author><name sortKey="Rogerson, Daniel T" sort="Rogerson, Daniel T" uniqKey="Rogerson D" first="Daniel T." last="Rogerson">Daniel T. Rogerson</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Biochemistry, University of Leicester, Leicester LE1 9HN, United Kingdom</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Biochemistry, University of Leicester, Leicester LE1 9HN</wicri:regionArea><wicri:noRegion>Leicester LE1 9HN</wicri:noRegion></affiliation></author><author><name sortKey="Bitton, Danny A" sort="Bitton, Danny A" uniqKey="Bitton D" first="Danny A." last="Bitton">Danny A. Bitton</name><affiliation wicri:level="4"><nlm:aff id="aff2">Paterson Institute for Cancer Research, University of Manchester, Manchester M20 4BX, United Kingdom</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Paterson Institute for Cancer Research, University of Manchester, Manchester M20 4BX</wicri:regionArea><orgName type="university">Université de Manchester</orgName><placeName><settlement type="city">Manchester</settlement><region type="nation">Angleterre</region><region nuts="2" type="region">Grand Manchester</region></placeName></affiliation></author><author><name sortKey="Miller, Crispin J" sort="Miller, Crispin J" uniqKey="Miller C" first="Crispin J." last="Miller">Crispin J. Miller</name><affiliation wicri:level="4"><nlm:aff id="aff2">Paterson Institute for Cancer Research, University of Manchester, Manchester M20 4BX, United Kingdom</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Paterson Institute for Cancer Research, University of Manchester, Manchester M20 4BX</wicri:regionArea><orgName type="university">Université de Manchester</orgName><placeName><settlement type="city">Manchester</settlement><region type="nation">Angleterre</region><region nuts="2" type="region">Grand Manchester</region></placeName></affiliation></author><author><name sortKey="Schwabe, John W R" sort="Schwabe, John W R" uniqKey="Schwabe J" first="John W. R." last="Schwabe">John W. R. Schwabe</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Biochemistry, University of Leicester, Leicester LE1 9HN, United Kingdom</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Biochemistry, University of Leicester, Leicester LE1 9HN</wicri:regionArea><wicri:noRegion>Leicester LE1 9HN</wicri:noRegion></affiliation></author><author><name sortKey="Tanaka, Kayoko" sort="Tanaka, Kayoko" uniqKey="Tanaka K" first="Kayoko" last="Tanaka">Kayoko Tanaka</name><affiliation wicri:level="1"><nlm:aff id="aff1">Department of Biochemistry, University of Leicester, Leicester LE1 9HN, United Kingdom</nlm:aff><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Biochemistry, University of Leicester, Leicester LE1 9HN</wicri:regionArea><wicri:noRegion>Leicester LE1 9HN</wicri:noRegion></affiliation></author></analytic><series><title level="j">Molecular Biology of the Cell</title><idno type="ISSN">1059-1524</idno><idno type="e-ISSN">1939-4586</idno><imprint><date when="2013">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>Fission yeast MOZART1 homologue Mzt1 associates with γ-tubulin and is found at MTOCs. It plays an essential role in microtubule regulation, as well as in septum formation and cytokinesis. Recombinant Mzt1 interacts directly with GCP3<sup>Alp6</sup>. 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sortKey="Holmes, S" uniqKey="Holmes S">S Holmes</name></author><author><name sortKey="Soues, S" uniqKey="Soues S">S Soues</name></author><author><name sortKey="Mann, M" uniqKey="Mann M">M Mann</name></author><author><name sortKey="Kilmartin, Jv" uniqKey="Kilmartin J">JV Kilmartin</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Xiong, Y" uniqKey="Xiong Y">Y Xiong</name></author><author><name sortKey="Oakley, Br" uniqKey="Oakley B">BR Oakley</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zheng, Y" uniqKey="Zheng Y">Y Zheng</name></author><author><name sortKey="Wong, Ml" uniqKey="Wong M">ML Wong</name></author><author><name sortKey="Alberts, B" uniqKey="Alberts B">B Alberts</name></author><author><name sortKey="Mitchison, T" uniqKey="Mitchison T">T Mitchison</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Zimmerman, S" uniqKey="Zimmerman S">S Zimmerman</name></author><author><name sortKey="Chang, F" uniqKey="Chang F">F Chang</name></author></analytic></biblStruct></listBibl></div1></back></TEI><affiliations><list><country><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Grand Manchester</li></region><settlement><li>Manchester</li></settlement><orgName><li>Université de Manchester</li></orgName></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Dhani, Deepsharan K" sort="Dhani, Deepsharan K" uniqKey="Dhani D" first="Deepsharan K." last="Dhani">Deepsharan K. Dhani</name></noRegion><name sortKey="Bitton, Danny A" sort="Bitton, Danny A" uniqKey="Bitton D" first="Danny A." last="Bitton">Danny A. Bitton</name><name sortKey="George, Gifty M" sort="George, Gifty M" uniqKey="George G" first="Gifty M." last="George">Gifty M. George</name><name sortKey="Goult, Benjamin T" sort="Goult, Benjamin T" uniqKey="Goult B" first="Benjamin T." last="Goult">Benjamin T. Goult</name><name sortKey="Miller, Crispin J" sort="Miller, Crispin J" uniqKey="Miller C" first="Crispin J." last="Miller">Crispin J. Miller</name><name sortKey="Rogerson, Daniel T" sort="Rogerson, Daniel T" uniqKey="Rogerson D" first="Daniel T." last="Rogerson">Daniel T. Rogerson</name><name sortKey="Schwabe, John W R" sort="Schwabe, John W R" uniqKey="Schwabe J" first="John W. R." last="Schwabe">John W. R. Schwabe</name><name sortKey="Tanaka, Kayoko" sort="Tanaka, Kayoko" uniqKey="Tanaka K" first="Kayoko" last="Tanaka">Kayoko Tanaka</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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